| Champions League Top Scorers 1955-2025 - Olympiakos Piraeus |
| 1 | Kostas Mitroglou | 11 | 2009 | 2014 |
| 2 | Predrag Djordjevic | 9 | 1997 | 2004 |
| 3 | Giovanni | 8 | 1999 | 2003 |
| 4 | Ieroklis Stoltidis | 7 | 2003 | 2009 |
| 5 | Stelios Giannakopoulos | 7 | 1997 | 2002 |
| 6 | Felipe Pardo | 5 | 2015 | 2017 |
| 7 | Nery Castillo | 5 | 2003 | 2006 |
| 8 | Alekos Alexandris | 5 | 1998 | 2002 |
| 9 | Nikos Anastopoulos | 5 | 1981 | 1983 |
| 10 | Alejandro Dominguez | 4 | 2013 | 2014 |