| Champions League Top Scorers 1955-2025 - Roma |
| 1 | Francesco Totti | 17 | 2001 | 2014 |
| 2 | Edin Dzeko | 15 | 2016 | 2018 |
| 3 | Daniele De Rossi | 8 | 2004 | 2018 |
| 4 | Mirko Vucinic | 8 | 2006 | 2008 |
| 5 | Christian Panucci | 5 | 2001 | 2008 |
| 6 | Antonio Cassano | 5 | 2002 | 2004 |
| 7 | Roberto Pruzzo | 5 | 1983 | 1983 |
| 8 | Cengiz Under | 4 | 2017 | 2018 |
| 9 | Gervinho | 4 | 2014 | 2015 |
| 10 | Marco Borriello | 4 | 2010 | 2010 |