| Champions League Top Scorers 1955-2025 - Panathinaikos |
| 1 | Antonis Antoniadis | 13 | 1969 | 1977 |
| 2 | Michalis Konstantinou | 9 | 2001 | 2004 |
| 3 | Krzysztof Warzycha | 8 | 1996 | 2000 |
| 4 | Dimitrios Saravakos | 8 | 1984 | 1991 |
| 5 | Giorgios Karagounis | 6 | 2000 | 2008 |
| 6 | Evangelos Mantzios | 5 | 2005 | 2008 |
| 7 | Angelos Basinas | 5 | 2000 | 2003 |
| 8 | Ezequiel Gonzalez | 4 | 2004 | 2005 |
| 9 | Emmanuel Olisadebe | 3 | 2001 | 2004 |
| 10 | Yannis Goumas | 3 | 2000 | 2001 |